What's wrong ? =?

What's wrong ? =What's the matter?

What's wrong ? =What's the matter?=what's the trouble?译为“怎么了；'出什么问题了”

what's wrong=what's the matter=what's up = what's the trouble?

口语里更适合用 what fk...正式用语 ＝ what happening? whats the matter. whats up...

What's wrong ？=What's the matter?
What's wrong ？=What's the difficulty?
What's wrong ？=What's the problem?

what's up?