能与您合个影吗？怎么用英语说？

May I take a photo with you ？
Do you mind we take a picture together?是另一种说法，都行啊（mind sb. do sth.）
还可以是Would you please take a photo with me?

Can I take a picture with you?

较委婉的表达：
Could I take a photo with you,please?
问题补充：很感谢你们的回答 如果我这样说Do you mind we take a picture together? 好么？
答复；不行。可改为:Do you mind if we take a picture together?
或；Do you mind our taking a picture together?

Would please photo with me?