求生物学高手用专业术语翻一下这句话，尤其是significance threshold的汉语解释

It is recommended that relatively lenient pool
significance thresholds are employed in two-stage selective
DNA pooling designs, where individual genotyping is performed
for confirmation of putative QTL linkages. This
strategy avoids the problems associated with setting stringent
significance thresholds for an initial genome scan and
instead controls false positives through accumulation of
evidence for the presence of a QTL.
谢谢大家的支持，这是一个关于QTl定位的题 应用统计学知识来减小微卫星假阳性，欢迎高手能讲出背后的东西。

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